Central Admin > Manage Services on Server
and check if the User Profile Service is started on the server or no, if it is not started, start the User Profile Service.
Restart SharePoint services
Do IISREST
If it is not solved, restart the server
and check if the User Profile Service is started on the server or no, if it is not started, start the User Profile Service.
Restart SharePoint services
Do IISREST
If it is not solved, restart the server